72 Results for "

Angelica lucida L.

" in MedChemExpress (MCE) Product Catalog:
Products (72)

72 Results for "Angelica lucida L." in MCE Product Catalog:

6
Isoimperatorin
Isoimperatorin
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6 Publications Verification
Cat. No.: HY-N0286
CAS No.: 482-45-1
Category:  

Neurological Disease Coumarins Phenylpropanoids Plants Umbelliferae Helogyne apaloidea Nutt. Disease Research Fields Cancer

Target:  

Cholinesterase (ChE) Bacterial

Isoimperatorin is a methanolic extract of the roots of Angelica dahurica shows significant inhibitory effects on acetylcholinesterase (AChE) with the IC50 of 74.6 μM.
4
Demethylsuberosin
Demethylsuberosin
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4 Cited Publications
Cat. No.: HY-N2488
CAS No.: 21422-04-8
Synonyms: 7-Demethylsuberosin
Category:  

Monophenols Coumarins Phenols Phenylpropanoids Plants Umbelliferae Disease Research Fields Inflammation/Immunology Echinacea angustifolia DC.

Target:  

Calcium Channel NO Synthase

Demethylsuberosin (7-Demethylsuberosin) is a coumarin compound found in Angelica gigas Nakai. Demethylsuberosin exerts antihypertensive effects by inhibiting the L-type CaV1.2 channel. Demethylsuberosin has antioxidant and anti-inflammatory activities. Demethylsuberosin also exhibits neuroprotective activities against glutamate-induced toxicity in primary cultured rat cortical cells .
3
Vanillic acid
Vanillic acid
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3 Cited Publications
Cat. No.: HY-N0708
CAS No.: 121-34-6
Category:  

Plants Endogenous metabolite Microorganisms Immune System Disorder Monophenols Ketones, Aldehydes, Acids Disease markers Phenols Umbelliferae Disease Research Fields Inflammation/Immunology Echinacea angustifolia DC.

Target:  

NF-κB Bacterial Endogenous Metabolite

Vanillic acid is a flavoring agent found in edible plants and fruits, also found in Angelica sinensis. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects .
2
α-Angelica lactone
α-Angelica lactone
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2 Cited Publications
Cat. No.: HY-N0548
CAS No.: 591-12-8
Category:  

Natural Products Dicerothamnus rhinocerotis Plants Umbelliferae Disease Research Fields Cancer

Target:  

Glutathione S-transferase

α-Angelica lactone is a naturally occurring anticarcinogen and an vinylogous nucleophile. α-Angelica lactone can give the chiral δ-amino γ,γ-disubstituted butenolide carbonyl derivatives and exhibitselectrophilic trapping at the γ-carbon. α-Angelica lactone exerts strong chemoprotective effects by selective enhancement of glutathione-S-thansferase (GST) and UDP-glucononosyltransferase (UGT) detoxification enzymes .
1
4-Hydroxyderricin
4-Hydroxyderricin
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1 Cited Publications
Cat. No.: HY-N7204
CAS No.: 55912-03-3
Category:  

Flavonoids Chalcones Monophenols Phenols Plants Umbelliferae Ondetia linearis Benth.

Target:  

Monoamine Oxidase Dopamine β-hydroxylase Apoptosis

4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is an orally active, potent selective MAO-B (Monoamine oxidase inhibitors) inhibitor with an IC50 of 3.43 μM. 4-Hydroxyderricin also mildly inhibits dopamine β (DBH)-hydroxylase activity. 4-Hydroxyderricin has antidepressant activity, anti-allergic, anti-diabetic, anti-oxidant, and antitumor effects. 4-Hydroxyderricin promotes apoptosis and cell cycle arrest through regulating PI3K/AKT/mTOR pathway in hepatocellular cells. 4-Hydroxyderricin inhibits osteoclast formation and accelerates osteoblast differentiation . 4-Hydroxyderricin is promising for research of inflammatory diseases .
1
Xanthoangelol
Xanthoangelol
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1 Cited Publications
Cat. No.: HY-111588
CAS No.: 62949-76-2
Purity:  99.88%
Category:  

Plants Infection Flavonoids Chalcones Phenols Polyphenols Umbelliferae Disease Research Fields Ondetia linearis Benth. Inflammation/Immunology

Target:  

Apoptosis Monoamine Oxidase Bacterial AMPK Caspase

Xanthoangelol, extracted from Angelica keiskei, suppresses obesity-induced inflammatory responses. Xanthoangelol possesses antibacterial activity. Xanthoangelol inhibits monoamine oxidases. Xanthoangelol induces apoptosis in neuroblastoma and leukemia cells .
1
Byakangelicol
Byakangelicol
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1 Cited Publications
Cat. No.: HY-N0074
CAS No.: 26091-79-2
Category:  

Coumarins Phenylpropanoids Plants Umbelliferae Helogyne apaloidea Nutt. Disease Research Fields Inflammation/Immunology

Target:  

COX

Byakangelicol, isolated from Angelica dahurica, inhibits interleukin-1beta (IL-1beta) -induced prostaglandin E2 (PGE2) release in A549 cells mediated by suppression of cyclooxygenase-2 (COX-2) expression and the activity of COX-2 enzyme. Byakangelicol has therapeutic potential as an anti-inflammatory agent on airway inflammation .
1
Alloimperatorin
Alloimperatorin
0 Images
1 Cited Publications
Cat. No.: HY-N2623
CAS No.: 642-05-7
Synonyms: Prangenidin
Category:  

Monophenols Coumarins Phenols Phenylpropanoids Plants Umbelliferae Helogyne apaloidea Nutt. Disease Research Fields Cancer

Target:  

Others

Alloimperatorin (Prangenidin), a coumarin compound, is extracted from Angelica dahurica. Alloimperatorin (Prangenidin) has antitumor activity .
1
3'-​O-​Acetylhamaudol
3'-​O-​Acetylhamaudol
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1 Cited Publications
Cat. No.: HY-N6892
CAS No.: 30358-88-4
Category:  

Monophenols Euryops arabicus Steud. ex Jaub. & Spach Ketones, Aldehydes, Acids Phenols Plants Umbelliferae Disease Research Fields Cancer

Target:  

Others

3'-O-Acetylhamaudol, isolated from Angelica polymorpha, exhibits anti-tumor activity through dual actions, anti-angiogenesis and intestinal intraepithelial lymphocyte activation .
Nodakenin
Nodakenin
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Cat. No.: HY-N0825
CAS No.: 495-31-8
Category:  

Coumarins Phenylpropanoids Plants Umbelliferae Disease Research Fields Inflammation/Immunology Bidens parviflora Willd.

Target:  

Cholinesterase (ChE)

Nodakenin is a major coumarin glucoside in the root of Angelica decusiva. Nodakenin inhibits acetylcholinesterase (AChE) activity with an IC50 of 84.7 μM .
Ligustilide
Ligustilide
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Cat. No.: HY-N0401
CAS No.: 4431-01-0
Category:  

Cardiovascular Disease Natural Products Neurological Disease Dicerothamnus rhinocerotis Plants Umbelliferae Disease Research Fields Inflammation/Immunology Echinacea angustifolia DC.

Target:  

Autophagy Apoptosis

Ligustilide is is a bioactive phthalide derivative isolated from Angelica sinensis and Chuanxiong. Ligustilide exhibits neuroprotective, anti-cancer, anti-inflammatory, and vasodilator effects .
Oxypeucedanin
Oxypeucedanin
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Cat. No.: HY-N0747
CAS No.: 737-52-0
Category:  

Cardiovascular Disease Chrysanthemum × morifolium (Ramat.) Hemsl. Coumarins Phenylpropanoids Plants Umbelliferae Disease Research Fields

Target:  

Potassium Channel PI3K NF-κB Akt p38 MAPK ERK COX NO Synthase JNK Apoptosis

Oxypeucedanin is a furanocoumarin derivative found in Angelica dahurica. Oxypeucedanin is an orally active PI3K/AKT/NF-κB, MAPK, and ROS inhibitor. Oxypeucedanin induces cell cycle arrest and apoptosis. Oxypeucedanin inhibits hKv1.5 channel currents (IC50: 76 nM). Oxypeucedanin exhibits anticancer, anti-inflammatory, antioxidant and antiarrhythmic activities .
Phellopterin
Phellopterin
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Cat. No.: HY-N2110
CAS No.: 2543-94-4
Category:  

Coumarins Phenylpropanoids Plants Umbelliferae Helogyne apaloidea Nutt. Disease Research Fields Inflammation/Immunology

Target:  

Akt Sirtuin Integrin STAT PI3K Apoptosis ERK PPAR PKC Toll-like Receptor (TLR) HIV

Phellopterin, an orally active furocoumarin with multiple biological activities. Phellopterin is a partial agonist of the central benzodiazepine receptors. Phellopterin exerts anti-inflammatory effects by upregulating SIRT1, downregulating ICAM-1 (reducing chronic inflammation, aiding diabetic ulcer healing), inhibiting STAT3 phosphorylation (easing atopic dermatitis inflammation), regulating Akt/PKC pathways (lowering TNF-α-induced VCAM-1 to block monocyte adhesion), and inhibiting TLR4/NF-κB pathway and macrophage M2 polarization (alleviating colitis-related cancers). Phellopterin suppresses ovarian cancer progression via inhibiting the PU.1/CLEC5A/PI3K-AKT loop (inducing cell cycle arrest, apoptosis, DNA damage). Phellopterin alleviates murine diabetes by promoting adipocyte differentiation and increasing PPARγ. Phellopterin also has anti-HSV-1 activity. Phellopterin can be used for studying anti-inflammation, anti-cancer (e.g., ovarian cancer, colitis cancer), blood glucose lowering, anti-diabetes, and anti-virus .
Cnidilin
Cnidilin
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Cat. No.: HY-N2272
CAS No.: 14348-22-2
Synonyms: Knidilin
Category:  

Chrysanthemum × morifolium (Ramat.) Hemsl. Coumarins Phenylpropanoids Plants Umbelliferae

Target:  

Others

Cnidilin (Knidilin) is isolated from the root of Angelica dahurica .
Byakangelicin
Byakangelicin
0 Images
Cat. No.: HY-N6022
CAS No.: 482-25-7
Category:  

Metabolic Disease Coumarins Phenylpropanoids Plants Umbelliferae Helogyne apaloidea Nutt. Disease Research Fields

Target:  

Others

Byakangelicin, one of the active compounds found in the roots of Angelica gigas, can serve as a modulator to improve brain accumulation of diverse active compounds (Umb, Cur, and Dox) and enhance therapeutic effects . Byakangelicin is likely to increase the expression of all PXR target genes (such as MDR1) and induce a wide range of agent-agent interactions. Byakangelicin can inhibit the effects of sex hormones, it may increase the catabolism of endogenous hormones .
2,3-Dihydroxypropyl decanoate
2,3-Dihydroxypropyl decanoate
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Cat. No.: HY-W099617
CAS No.: 2277-23-8
Synonyms: 1-Decanoyl-rac-glycerol
Target:  

Biochemical Assay Reagents Drug Derivative

Research Areas:  

Others

2,3-Dihydroxypropyl decanoate (1-Decanoyl-rac-glycerol) is a derivative of Decanoic acid (HY-W015309) and a non-ionic surfactant, with an IC50 > 100 μM against Shp2-PTP, VHR and HePTP. 2,3-Dihydroxypropyl decanoate is found in the roots of Angelica dahurica (Baizhi). 2,3-Dihydroxypropyl decanoate acts as a component of reverse micelle systems for the encapsulation of proteins and nucleic acids .
Oxyimperatorin
Oxyimperatorin
0 Images
Cat. No.: HY-N4273
CAS No.: 35740-18-2
Synonyms: (±)-Heraclenin
Category:  

Chrysanthemum × morifolium (Ramat.) Hemsl. Other Diseases Coumarins Phenylpropanoids Plants Umbelliferae Disease Research Fields

Target:  

Others

Oxyimperatorin ((±)-Heraclenin) is a coumarin isolated from Angelica dahurica.
(-)-Anomalin
(-)-Anomalin
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Cat. No.: HY-N0947
CAS No.: 4970-26-7
Synonyms: (-)-Praeruptorin B
Category:  

Salvia hypargeia Fisch. & C.A.Mey. Coumarins Phenylpropanoids Plants Umbelliferae Disease Research Fields Inflammation/Immunology Artemisia vulgaris L.

Target:  

Others

(-)-Anomalin ((-)-Praeruptorin B) is a coumarin derivative isolated from the root of Angelica anomala .
(Rac)-Byakangelicin
(Rac)-Byakangelicin
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Cat. No.: HY-N0075
CAS No.: 19573-01-4
Category:  

Ruta graveolens Linn. Rutaceae Metabolic Disease Coumarins Phenylpropanoids Plants Disease Research Fields

Target:  

Others

(Rac)-Byakangelicin is a racemate of Byakangelicin mainly isolated from the genus Angelica. Byakangelicin is an aldose-reductase inhibitor with an IC50 value of 6.2 μM .
Vanillic acid (Standard)
Vanillic acid (Standard)
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Cat. No.: HY-N0708R
CAS No.: 121-34-6
Category:  

Microorganisms Immune System Disorder Monophenols Ketones, Aldehydes, Acids Disease markers Phenols Plants Umbelliferae Endogenous metabolite Echinacea angustifolia DC.

Target:  

Reference Standards NF-κB Bacterial Endogenous Metabolite

Vanillic acid (Standard) is the analytical standard of Vanillic acid. This product is intended for research and analytical applications. Vanillic acid is a flavoring agent found in edible plants and fruits, also found in Angelica sinensis. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects .
Assay Types